Isotopically Labeled Compounds
Medchemexpress LLC Phenacetin-13C | 72156-72-0 | 99.9% | 50 MG
Phenacetin-13C is the 13C labeled Phenacetin, a non-opioid analgesic/antipyretic agent that acts as a selective COX-3 inhibitor. It is used as a probe for cytochrome P450 enzymes CYP1A2 in human liver microsomes and in rats. This compound serves as a tracer and internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS.
- 13C labeled compound
- Non-opioid analgesic/antipyretic agent
- Selective COX-3 inhibitor
- Probe for cytochrome P450 enzymes
- Tracer for quantitative analysis
- Internal standard for quantitative analysis
Medchemexpress LLC Pyridostigmine-d6 bromide | 2375858-08-3 | 100.0% | 5 MG
Pyridostigmine-d6 bromide is a deuterium-labeled Pyridostigmine, functioning as a parasympathomimetic and a reversible cholinesterase inhibitor. It is used as a tracer and an internal standard in quantitative analyses.
- Deuterium-labeled compound
- Functions as a parasympathomimetic and reversible cholinesterase inhibitor
- Used as a tracer for quantitative analysis
- Serves as an internal standard in analytical techniques like NMR, GC-MS, and LC-MS
- Incorporates stable heavy isotopes
Medchemexpress LLC D-Glucose-13C2 | 201741-04-0 | 98.0% | 50 MG
D-Glucose-13C2 is a 13C labeled D-Glucose, a vital monosaccharide and carbohydrate in biology. It plays a critical role in general metabolism and functions as a signaling molecule for cellular metabolic status and stress response. This compound is valuable as a tracer and internal standard for quantitative analysis in various analytical methods.
- 13C labeled D-Glucose.
- Important carbohydrate and monosaccharide in biology.
- Critical for general metabolism.
- Serves as a signaling molecule for cellular metabolic status and stress response.
- Can be used as a tracer in drug development.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Adenine-d (6-aminopurine-d1) | 109923-52-6 | 99.9% | 5 MG
Adenine-d is a deuterium-labeled adenine, a purine nucleobase essential for DNA and RNA. It plays a crucial role in biochemistry, including cellular respiration, ATP formation, and protein synthesis. This compound can be used as a tracer or as an internal standard for quantitative analysis.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Duloxetine-d7 | 919514-01-5 | 97.3% | 1 MG
Duloxetine-d7 is the deuterium labeled form of Duloxetine, a serotonin-norepinephrine reuptake inhibitor with a Ki of 4.6 nM. It is used for the treatment of major depressive disorder and generalized anxiety disorder (GAD). Stable heavy isotopes, such as deuterium, are incorporated into drug molecules for use as tracers in drug development and to potentially affect pharmacokinetic and metabolic profiles.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC 5Z,8Z,11Z,14Z-Eicosatetraenoic-16,16,17,17,18,18,19,19,20,20,20-d11 acid | 2692624-11-4 | 98.0% | 315.53 | 50 MG
Arachidonic acid-d11 is the deuterium labeled Arachidonic acid. It is an essential fatty acid and a major constituent of biomembranes. This product is provided as a colorless to light yellow liquid solution.
- Deuterium labeled
- Essential fatty acid
- Major constituent of biomembranes
- Colorless to light yellow liquid
- Purity of 98.0%
- Store at -20°C for up to 2 years
Medchemexpress LLC 1-Bromotridecane-d4 10mg
1-Bromotridecane-d4 is the deuterium labeled 1-Bromotridecane[1]
Medchemexpress LLC Devimistat-d10 | 2586055-61-8 | C22H18D10O2S2 | 25 MG
Devimistat-d10 is a deuterium-labeled compound, serving as an internal standard and tracer for quantitative analysis in various analytical techniques.
- Deuterium-labeled compound
- Suitable as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- For research use only
- High purity (99.79%)
- Solid, white to off-white appearance
Revvity Health Sciences Inc Iodine-125 Radionuclide, 10mCi, Specific Activity: ~17Ci/mg, 0.1M NaOH (pH 12-14), Concentration: >350mCi/mL
Iodine-125 Radionuclide, 10mCi, Specific Activity: ~17Ci/mg, 0.1M NaOH (pH 12-14), Concentration: >350mCi/mL
Medchemexpress LLC Dibenzothiophene-d8 | 33262-29-2 | 5 MG
Dibenzothiophene-d8 is a deuterium-labeled version of Dibenzothiophene, a noncompetitive CYP1A inhibitor that interacts with the AHR pathway. It is primarily used to study the mechanism of developmental toxicity. Dibenzothiophene-d8 can serve as a tracer or internal standard for quantitative analysis.
- Deuterium-labeled compound
- Functions as a tracer
- Serves as an internal standard for quantitative analysis via NMR, GC-MS, or LC-MS
- Useful for studying developmental toxicity mechanisms
- Deuteration potentially affects pharmacokinetic and metabolic profiles
Medchemexpress LLC Dotriacontane-d66 | 62369-68-0 | 99.1% | 517.27 | 100 MG
Dotriacontane-d66 is a deuterium labeled Dotriacontane. It can be used as a tracer and as an internal standard for quantitative analysis. Deuteration has gained attention due to its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer and internal standard
- Suitable for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuteration may affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Triphenylene-d12 | 17777-56-9 | 98% | 240.36 | 100 MG
Triphenylene-d12 is the deuterium labeled triphenylene, intended for research use only. This compound serves as a tracer and an internal standard for quantitative analysis, suitable for methods like NMR, GC-MS, or LC-MS.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes incorporated into drug molecules for quantitation during drug development
- Deuteration can affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Rivaroxaban-d4 (BAY 59-7939-d4) | 1132681-38-9 | 98.7% | 439.91 | 1 MG
Rivaroxaban-d4 (BAY 59-7939-d4) is a deuterium-labeled form of Rivaroxaban, a highly potent, selective, and direct Factor Xa (FXa) inhibitor. It demonstrates significant anti-FXa potency with an IC50 of 0.7 nM and a Ki of 0.4 nM.
- Deuterium labeled compound
- Potent, selective, and direct Factor Xa (FXa) inhibitor
- Useful as a tracer or internal standard
- Suitable for quantitative analysis by NMR, GC-MS, or LC-MS
- For research use only
Medchemexpress LLC N-Fmoc-leucine-d3 | 538372-74-6 | 99.3% | 356.43 | C21H20D3NO4 | 100 MG
Deuterated Fmoc-protected leucine is a stable-isotope labeled amino acid derivative used as a tracer and internal standard for quantitative analysis by NMR, GC-MS, and LC-MS. It is supplied as a white to off-white solid of high purity suitable for analytical and research applications.
- Deuterium-labeled Fmoc-protected leucine for isotope-dilution quantitation.
- Suitable as tracer and internal standard for NMR, GC-MS, and LC-MS.
- High purity (≈99.3%) for accurate analytical results.
- White to off-white solid form for easy handling and storage.
- Molecular weight 356.43 and CAS number 538372-74-6.